SEMI Side Effects May Include Download

About This Game

SEMI Side Effects May Include is a chaotic and hilarious cooperative action-platformer that challenges you and your friends to escape a bizarre medical facility. Developed by Two Horn Unicorn, the game casts you as patients in a deranged clinic where the only way out is through experimental treatments. It is a physics-based brawler where teamwork is essential, yet sabotage is often an accidental or intentional byproduct of the madness.

The gameplay mechanics revolve around “Pill Roulette,” where taking experimental drugs grants you incredible superpowers at a high cost. These abilities, such as Alice’s Syndrome (size changing) or Bipolar Force (shifting between invulnerability and ragdoll physics), come with unpredictable side effects that can turn a simple escape into a disaster. You must navigate procedurally generated rooms filled with shifting gravity, moving walls, and hostile guards, all while managing your sanity and using improvised weapons like plungers or bottles to fight back.

With its cartoonish 3D art style and exaggerated ragdoll physics, S.E.M.I. thrives on unscripted moments and emergent comedy. The game features online co-op for up to 4 players, pushing you to communicate via voice chat as you solve puzzles and survive randomized hazards. After every successful escape (or spectacular failure), you receive a detailed medical report of your antics. It is a perfect choice for gamers who love the unbridled chaos of party-style physics brawlers mixed with the progression of a roguelite adventure.

Action
Indie
Arcade
All Games

System Requirements

• Operating System: Windows 10, 11 (64-bit)
• Processor: Intel Core i5 series / Ryzen series
• RAM: 8 GB RAM
• Graphics: NVIDIA GTX 960 / AMD R9 290
• Storage: 3 GB available space

Direct Download Link
Size: 955 MB